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Memory Lane: A neuro-exergame to mitigate cognitive decline in later life

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R41AG053120-01
Agency Tracking Number: R41AG053120
Amount: $149,999.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: NIA
Solicitation Number: PA15-270
Solicitation Year: 2015
Award Year: 2016
Award Start Date (Proposal Award Date): 2016-09-15
Award End Date (Contract End Date): 2017-10-31
Small Business Information
5 3RD ST # 300
Troy, NY 12180-3205
United States
DUNS: 787314058
HUBZone Owned: No
Woman Owned: Yes
Socially and Economically Disadvantaged: No
Principal Investigator
 (518) 428-2174
Business Contact
Phone: (518) 428-2174
Research Institution

DESCRIPTION provided by applicant st Playable Productions and Union College propose to develop a commercializable product combining physical exercise and cognitive activities through interactive gaming on a stationary bicycle to help prevent cognitive decline and dementia in older adults The Interactive Physical and Cognitive Exercise System iPACES developed by Union Collegeandapos s Healthy Aging and Neuropsychology Lab is the first system to combine physical and cognitive interventions and has already proven to have a greater cognitive benefit to older adults than either of these two interventions alone While behavioral interventions are unlikely to completely prevent or halt dementia there is the potential for synergistic physical and cognitive exercise specifically to reduce the risk of onset dementia or slow progression Creating an affordable and easily distributed product will enable wide access to this intervention while also furthering understanding of what combinations have biggest impact This Phase I project includes the development of a game that combines physical and cognitive exercise a hardware configuration that is safe for older adults and suited for in home installation and the further collection of user data to inform further developments in engaging design Participants will be recruited from area retirement communities and advertising and screened for suitability Participants are assessed after two weeks of playing the cognitive game without exercise then as participants engage in the full experience they are assessed at and weeks Normative individuals interested in maintaining brain health patients who are prescribed iPACES to slow or ameliorate cognitive decline retirement and assisted living communities are all potential beneficiaries of the dementia treatment The incidence of dementia in North America is projected to nearly triple from million cases in to million by with a worldwide increase from to million over the same time period Considering multiple causes of dementia no known cure and minimal benefit from medication behavioral interventions to improve brain health are a critical component for extending quality of life for patients families and their support systems

PUBLIC HEALTH RELEVANCE Memory Lane c is a neuro exergame that utilizes an interactive physical and cognitive exercise system iPACES c to help prevent or ameliorate cognitive decline and dementia in older adults This project extends prior research on the benefits of interactive phsycial and cognitive exercise Anderson Hanley et al as well as promising preliminary data from a single bout pilot study using Memory Lane with older adults which found greater cognitive benefit of neuro exergaming than either exercise or gaming alone Anderson Hanley The goal is create an accessible easily distributed product that can protect against and ameliorate cognitive decline to improve quality of life for an aging population

* Information listed above is at the time of submission. *

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