Development of a Low Profile Dual Hormone Patch Pump with Novel Occlusion Sensor

Development of a Low Profile Dual Hormone Patch Pump
with Novel Occlusion Sensor
Project Summary
The Specific Aim of this project is to develop a discrete low profile dual hormone drug
delivery system using SFC Fluidics enabling microfluidic technologies A dual ePump will be
developed in which a single ePump body will independently and accurately deliver both insulin
and glucagon from two separate reservoirs Latching micro valve sets will independently and
safely control the delivery of each hormone and a flow confirmation sensor will identify dosing
errors from either occlusions or electrical mechanical failures Phase I will see the development
of an early prototype with control system and a dosing accuracy of for nL to L dosing
volumes will be targeted During Phase II SFC Fluidics will work closely with clinicians and
drug formulation glucose sensor and control algorithm developers to develop a robust and
reliable artificial pancreas Project Narrative
The proposed dual drug delivery system will have the necessary safety features and low
dose accuracy to meet the need for insulin and glucagon dual hormone delivery to type
diabetics including children and adolescents to greatly improve the quality of life for this
significant and growing at risk group