Physiologically Compatible Hemodialysis Through Advanced Dialysate Regeneration

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 90BISB0002
Agency Tracking Number: 90BISB0002
Amount: $574,714.00
Phase: Phase II
Program: SBIR
Awards Year: 2017
Solicitation Year: 2016
Solicitation Topic Code: N/A
Solicitation Number: HHS-2016-ACL-NIDILRR-BISB-0182
Small Business Information
2611 SW Third Ave, STE250F, Portland, OR, 97201-4957
DUNS: 799155523
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Takuji Tsukamoto
 (503) 352-0262
Business Contact
 Andrea Adamson
Title: Vice President
Phone: (503) 352-0262
Research Institution
This project develops an advanced, portable hemodialysis regeneration system that significantly enhances the quality of life of end-stage renal disease (ESRD) patients. ESRD impairs physiological systems and functions, and is associated with disability, high morbidity and mortality. Hemodialysis is prescribed for the majority of individuals in the final stages of renal failure. Minimizing the loss of nutrients and improving dialysis delivery (length, frequency, and location) enables individuals with ESRD to feel better, have more energy, work more, and engage in activities in their communities. Project investigators use surface chemistry and material science techniques to develop an advanced dialysate regeneration system able to remove a broad spectrum of uremic toxins while minimizing the loss of nutrients such as amino acids, vitamins, and essential ions. Technical objectives include: (1) performing scale-up production of the components of the advanced dialysate regeneration system (DRS-2); (2) designing and constructing the prototype module (cartridge) to house the DRS-2; (3) proving the safety and efficacy of the DRS-2 in vitro; (4) performing overall efficacy and quality tests of the DRS-2 using spent dialysate; and (5) evaluating and summarizing Phase II processes and results.

* Information listed above is at the time of submission. *

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