You are here

HIGH-SPEED GAS CHROMATOGRAPHY AS AN IMPROVED CHEMICAL INSTRUMENT

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: N/A
Agency Tracking Number: 27329
Amount: $300,000.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Timeline
Solicitation Year: N/A
Award Year: 1995
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
912 N Main St Ste 14
Ann Arbor, MI 48104
United States
DUNS: N/A
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Mark A Klemp
 (313) 663-5150
Business Contact
Phone: () -
Research Institution
N/A
Abstract

GAS CHROMATOGRAPHY IS ONE OF THE MOST WIDELY USED METHODS FOR THE CHEMICAL ANALYSIS OF ORGANIC COMPOUNDS. THE METHOD HAS BROAD APPLICABILITY, A VERY LARGE CONCENTRATION RANGE, AND EXCELLENT PRECISION AND ACCURACY. HOWEVER, IT IS QUITE SLOW REQUIRING SEVERAL MINUTES OR MORE PER ANALYSIS USING CONVENTIONAL INSTRUMENTATION AND TECHNIQUES. BY THE USE OF SHORT CAPILLARY SEPARATION COLUMNS OPERATED AT UNUSUALLY HIGH GAS VELOCITIES, ANALYSIS TIMES CAN BE REDUCED TO A FEW SECONDS IN MANY CASES. HOWEVER, OPERATION IN THIS TIME DOMAIN REQUIRES THE DEVELOPMENT OF HIGH-SPEED INLET SYSTEMS TO OBTAIN SUFFICIENTLY NARROW SAMPLE BAND WIDTHS. IN ADDITION, OPERATION AT VERY HIGH SPEED RESULTS IN SIGNIFICANT LOSS OF RESOLUTION. RESEARCHERS ARE DEVELOPING A HIGH-SPEED GAS CHROMATOGRAPHY INSTRUMENT THAT USES A CRYOFOCUSSING INLET SYSTEM CAPABLE OF PRECONCENTRATING A VAPOR SAMPLE AND INTRODUCING IT TO THE SEPARATION COLUMN ASA VERY NARROW PLUG. TO COMPENSATE FOR THE LOSS IN RESOLUTION, THE INSTRUMENT USES TANDEM ENSEMBLES OF CAPILLARY COLUMNS HAVING DIFFERENT STATIONARY PHASES. BY DIFFERENTIALLY ADJUSTING THE GAS FLOW RATES OR TEMPERATURES OF THE INDIVIDUAL COLUMNS, SELECTIVITY CAN BE ADJUSTED FOR SPECIFIC APPLICATIONS. ANALYSIS TIMES OF A FEW SECONDS SHOULD BE ACHIEVED.

* Information listed above is at the time of submission. *

US Flag An Official Website of the United States Government