Portable System for Rapid Detection of Toxins

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$153,339.00
Award Year:
2004
Program:
SBIR
Phase:
Phase I
Contract:
1R43ES012847-01A1
Award Id:
71597
Agency Tracking Number:
ES012847
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
CIENCIA, INC., 111 ROBERTS ST, STE K, EAST HARTFORD, CT, 06108
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
SALVADOR FERNANDEZ
(860) 528-9737
fernandez@ciencia.com
Business Contact:
ARTURO PILAR
(860) 528-9737
APILAR@CIENCIA.COM
Research Institution:
n/a
Abstract
DESCRIPTION (provided by applicant): The goal of the proposed effort is to develop a biosensor for rapid, on-site measurement of chemical environmental contaminants. The crux of the innovation is to use grating-coupled surface plasmon resonance (GCSPR) transduction in conjunction with a microarray transducer chip and an imaging CCD detector to implement a system capable of highly multiplexed detection of many analytes with high sensitivity in a small portable, rugged, low-cost package suitable for field use by minimally trained personnel. The proposed device will solve two of the most important shortcomings of present technology for field environmental analysis; namely, the limitation of current systems to the detection of a single analyte or a single class of closely related compounds, and the limited sensitivity and accuracy of field assays. In addition, we expect that the proposed system will materially increase the ease and speed with which these assays can be performed in the field. The objectives of the Phase I effort are to build a breadboard prototype of a GCSPR imaging system to assess its feasibility for multiplexed detection, and to demonstrate the operation of the system with a prototype assay using polycyclic aromatic hydrocarbons (PAH) as an analyte model system. Potential applications include environmental testing, clinical diagnostics, homeland defense applications and the life sciences research market.

* information listed above is at the time of submission.

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