System for Multiplex Real-Time Analysis of Nucleic Acids

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R43HG003025-01A2
Agency Tracking Number: HG003025
Amount: $170,978.00
Phase: Phase I
Program: SBIR
Awards Year: 2005
Solicitation Year: 2005
Solicitation Topic Code: N/A
Solicitation Number: PHS2005-2
Small Business Information
Ciencia, Inc., 111 Roberts St, Ste K, East Hartford, CT, 06108
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: Y
Principal Investigator
 (860) 528-9737
Business Contact
Phone: (860) 528-9737
Research Institution
DESCRIPTION (provided by applicant): The objective of this Phase I project is to test the feasibility of biochip imaging system which will vary the temperature of the arrays and perform real-time imaging and quantification during PCR and probe meltoff. A specialized microarray of discrete hydroge! Compartments for array-based PCR amplification will be tested with the prototype instrument. The technology is expected to be appropriate for significant applications such as gene expression, polymorphism scoring and microbial detection and typing. Consumption of sample and reagents will be minimized, because significant multiplex factors can be realized in small volumes. The expected outcome of this project is the specification of a versatile instrument for research or diagnostics that could be brought into the development phase.

* Information listed above is at the time of submission. *

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