DEVELOPMENT OF ALTERNATIVE AFFINITY CAPTURE REAGENTS FOR CANCE
Small Business Information
8333 HICKMAN MILLS DR, KANSAS CITY, MO, 64132-2515
AbstractMany of the antibodies produced for cancer research are poorly characterized, exhibit suboptimal affinity or selectivity, and are time-consuming and expensive to produce. Alternative affinity capture reagents are therefore needed as reproducible, highly characterized, rapid, and cost-effective substitutes for monoclonal antibodies. As a platform for creating affinity capture reagents, Aptakon has developed a 10 kD protein scaffold with loops similar to the complementarity determining region of the immunoglobulin domain. Aptakon aims to construct plasmid and phagemid libraries of variant scaffolds
* information listed above is at the time of submission.