DEVELOPMENT OF ALTERNATIVE AFFINITY CAPTURE REAGENTS FOR CANCE

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$149,857.00
Award Year:
2010
Program:
SBIR
Phase:
Phase I
Contract:
N43CO201000071
Agency Tracking Number:
N43CO201000071
Solicitation Year:
2010
Solicitation Topic Code:
NCI
Solicitation Number:
PHS2010-1
Small Business Information
APTAKON, INC.
8333 HICKMAN MILLS DR, KANSAS CITY, MO, 64132-2515
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
809981108
Principal Investigator:
Keith Kropp
(816) 510-7674
Business Contact:
(816) 510-7674
Research Institution:
n/a
Abstract
Many of the antibodies produced for cancer research are poorly characterized, exhibit suboptimal affinity or selectivity, and are time-consuming and expensive to produce. Alternative affinity capture reagents are therefore needed as reproducible, highly characterized, rapid, and cost-effective substitutes for monoclonal antibodies. As a platform for creating affinity capture reagents, Aptakon has developed a 10 kD protein scaffold with loops similar to the complementarity determining region of the immunoglobulin domain. Aptakon aims to construct plasmid and phagemid libraries of variant scaffolds

* information listed above is at the time of submission.

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