DEVELOPMENT OF ALTERNATIVE AFFINITY CAPTURE REAGENTS FOR CANCE

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N43CO201000071
Agency Tracking Number: N43CO201000071
Amount: $149,857.00
Phase: Phase I
Program: SBIR
Awards Year: 2010
Solicitation Year: 2010
Solicitation Topic Code: NCI
Solicitation Number: PHS2010-1
Small Business Information
8333 HICKMAN MILLS DR, KANSAS CITY, MO, 64132-2515
DUNS: 809981108
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Keith Kropp
 (816) 510-7674
Business Contact
Phone: (816) 510-7674
Research Institution
N/A
Abstract
Many of the antibodies produced for cancer research are poorly characterized, exhibit suboptimal affinity or selectivity, and are time-consuming and expensive to produce. Alternative affinity capture reagents are therefore needed as reproducible, highly characterized, rapid, and cost-effective substitutes for monoclonal antibodies. As a platform for creating affinity capture reagents, Aptakon has developed a 10 kD protein scaffold with loops similar to the complementarity determining region of the immunoglobulin domain. Aptakon aims to construct plasmid and phagemid libraries of variant scaffolds

* Information listed above is at the time of submission. *

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