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SBIR Phase II: Comprehensive Database Resource on Protein Localization

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: 0239206
Agency Tracking Number: 0239206
Amount: $499,407.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 2003
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
117 East 55th Street, New York, NY, 10022
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Christopher Larsen
 () -
Business Contact
Phone: () -
Research Institution
This Small Business Innovation Research (SBIR) Phase II Project proposes to develop the database and associated software to enable analysis of protein trafficking and localization. The system will be designed to enable drug discovery researchers to identify, elucidate, eliminate and design leads and targets, while facilitating the general training of researchers. During the Phase I work, proteins involved in trafficking and diseases related to mislocalization were identified, and a relational database to house information on protein trafficking was constructed. Curation interface applications were created to allow remote data entry, and graphical user interfaces designed to maximize the utility of the information. The objective of this Phase II Project is to exhaustively populate the database from the primary journal literature. Selection of proteins involved in protein trafficking will be guided by relevant human diseases and corresponding drug discovery efforts. The commercial application of this project is in the area of biological informatics. The potential users of the biological database to be developed in this project would include pharmaceutical and drug discovery companies.

* Information listed above is at the time of submission. *

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