Single Cell Micro-chamber Array analysis

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R43GM090515-01
Agency Tracking Number: GM090515
Amount: $99,839.00
Phase: Phase I
Program: SBIR
Awards Year: 2010
Solicitation Year: 2010
Solicitation Topic Code: NIGMS
Solicitation Number: PHS2010-2
Small Business Information
EANDM DEVICES, INC.
EANDM DEVICES, INC., 2973 Santos Lane # 301, Walnut Creek, CA, 94597
DUNS: 828989140
HUBZone Owned: N
Woman Owned: Y
Socially and Economically Disadvantaged: N
Principal Investigator
 ERI TAKAHASHI
 () -
Business Contact
 CHUL WON
Phone: (510) 409-0245
Email: wonchul@eandmdevices.com
Research Institution
N/A
Abstract
DESCRIPTION (provided by applicant): Abnormalities in the cytosol of subpopulations of cells are often a hallmark of pathology. Most analysis methods will only provide information on the cytosol of cell populations as a whole, not for individual cells or subpopulations of cells. To overcome this, we propose to develop Single Cell Micro-chamber Array (SiCMA) technology. This approach is based on preliminary studies in the laboratory of Dr. Kuypers at CHORI to use microchamber arrays to report on the stochastic distribution of cytosolic components. In this Phase I SBIR we aim to prove the principle of this approach and set the stage for further development in a joint effort between EandM devices and CHORI. The successful completion of the proposed studies will establish our ability to measure cytosolic components correlated with cell surface markers in a complex cell population, and provide the basis for commercialization of this technology.

* information listed above is at the time of submission.

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