NOVEL PYROGEN REMOVAL SYSTEM

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R43DK061780-01
Agency Tracking Number: DK061780
Amount: $110,700.00
Phase: Phase I
Program: SBIR
Awards Year: 2002
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
COMPACT MEMBRANE SYSTEMS, INC.
325 WATER STREET, WILMINGTON, DE, 18904
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 STUART NEMSER
 (302) 999-7996
 stuart.nemser@compactmembrane.com
Business Contact
 STUART NEMSER
Phone: (302) 999-7996
Email: NLESTER@COMPACTMEMBRANE.COM
Research Institution
N/A
Abstract
DECRIPTION (Provided by applicant): Pyrogen-free water (PFW) is required in many applications. Laboratories use it as solvent for compound preparation, culture media, and equipment rinse. Hospitals use it for cleaning to prepare solutions for injections, lV's, and hemodialysis. Pharmaceutical manufacturers use it to formulate injectable drug preparations. Pyrogens, or fever-inducers, are derived from metabolic byproducts of bacteria, molds, yeasts, viruses, and certain chemicals. Current technology used to prepare PFW include distillation, reverse osmosis, and ultrafiltration. Overall these processes are complicated, prone to failure, and in many cases do not remove sufficient pyrogens and are not ideal for small scale facilities. In this program, Compact Membrane Systems (CMS) has identified a simple (push one button) system that is easily integrated into existing systems for pyrogen removal. The basis of the CMS technology is a novel oxidizing system that both kills microorganisms and oxidizes their endotoxins. In Phase I we will develop this novel oxidizing system and demonstrate superior pyrogen removal compared to existing technologies. PROPOSED COMMERCIAL APPLICATION: Water for Injection including Kidney Dialysis water and pharmaceutical water.

* information listed above is at the time of submission.

Agency Micro-sites

US Flag An Official Website of the United States Government