TWO MILLIMETER PET SCINTILLATION DETECTOR ARRAY

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1991
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
16783
Agency Tracking Number:
16783
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
810 Innovation Dr, Knoxville, TN, 37932
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Ward Digby
Principal Investigator
(615) 966-7539
Business Contact:
() -
Research Institute:
n/a
Abstract
THE RESEARCH WILL LEAD TO THE DEVELOPMENT OF A VERY HIGH-RESOLUTION SCINTILLATION DETECTOR ARRAY FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING. TWO ALTERNATIVE SCHEMES WILL BE INVESTIGATED TO IMPROVE THE IMAGE RESOLUTION AND QUANTITATIVE ACCURACY OF PET. THE FIRST WILL BE AN ADVANCE TO THE CURRENT "BLOCK" DETECTOR CONCEPT BASED ON AN 8X8 ARRAY OF BISMUTH GERMANATE (BGO), OR LEAD SULFATE (PBSO4) SCINTILLATION CRYSTALS COUPLED THROUGH A LIGHT GUIDE TO FOURPHOTOMULTIPLIER TUBES. THE CRYSTALS WILL BE SPACED 3MM APART BOTH AXIALLY AND TRANSAXIALLY AND SHOULD PROVIDE RESOLUTION OF APPROXIMATELY 2.5MM IN ALL DIRECTIONS. THE SECOND DETECTOR CONFIGURATION WILL USE SIMILAR SIZED ARRAY OF SCINTILLATORS BUT COUPLED TO A GRID OF SILICON PHOTODIODES TO DETERMINE THE INTERACTION DETECTOR, WITH A SINGLE LARGE PMT TO PROVIDE THE TIMING SIGNALS. PROTOTYPE DETECTORS WILL BE CUT FROM SOLID BLOCKS OF SCINTILLATOR AND TESTED FOR THE PHOTOELECTRON YIELD AND EVENT POSITIONING CHARACTERISTICS. THE LIGHT GUIDE WILL BE ADJUSTED TO PROVIDE MAXIMUM DIFFERENTIATION IN THE POSITIONING SIGNALS BETWEEN THE VARIOUS CRYSTALS OF THE ARRAY WHILE MAINTAINING HIGH LIGHT OUTPUT. ONCE THE LIGHTGUIDE DESIGNS HAVE BEEN DETERMINED, MORE DETAILED MEASUREMENTS WILL BE PERFORMED TO CHARACTERIZE THE POSITIONING ACCURACY, TIME RESOLUTION, ENERGY RESOLUTION, AND EFFICIENCY. THIS RESEARCH SHOULD PRODUCE THE HIGHEST RESOLUTION PET MODULAR DETECTOR DESIGN BASED ON FOUR PHOTOMULTIPLIERS. THE RESEARCH WILL LEAD TO THE DEVELOPMENT OF A VERY HIGH-RESOLUTION SCINTILLATION DETECTOR ARRAY FOR POSITRON EMISSION TOMOGRAPHY (PET) IMAGING. TWO ALTERNATIVE SCHEMES WILL BE INVESTIGATED TO IMPROVE THE IMAGE RESOLUTION AND QUANTITATIVE ACCURACY OF PET. THE FIRST WILL BE AN ADVANCE TO THE CURRENT "BLOCK" DETECTOR CONCEPT BASED ON AN 8X8 ARRAY OF BISMUTH GERMANATE (BGO), OR LEAD SULFATE (PBSO4) SCINTILLATION CRYSTALS COUPLED THROUGH A LIGHT GUIDE TO FOURPHOTOMULTIPLIER TUBES. THE CRYSTALS WILL BE SPACED 3MM APART BOTH AXIALLY AND TRANSAXIALLY AND SHOULD PROVIDE RESOLUTION OF APPROXIMATELY 2.5MM IN ALL DIRECTIONS. THE SECOND DETECTOR CONFIGURATION WILL USE SIMILAR SIZED ARRAY OF SCINTILLATORS BUT COUPLED TO A GRID OF SILICON PHOTODIODES TO DETERMINE THE INTERACTION DETECTOR, WITH A SINGLE LARGE PMT TO PROVIDE THE TIMING SIGNALS. PROTOTYPE DETECTORS WILL BE CUT FROM SOLID BLOCKS OF SCINTILLATOR AND TESTED FOR THE PHOTOELECTRON YIELD AND EVENT POSITIONING CHARACTERISTICS. THE LIGHT GUIDE WILL BE ADJUSTED TO PROVIDE MAXIMUM DIFFERENTIATION IN THE POSITIONING SIGNALS BETWEEN THE VARIOUS CRYSTALS OF THE ARRAY WHILE MAINTAINING HIGH LIGHT OUTPUT. ONCE THE LIGHTGUIDE DESIGNS HAVE BEEN DETERMINED, MORE DETAILED MEASUREMENTS WILL BE PERFORMED TO CHARACTERIZE THE POSITIONING ACCURACY, TIME RESOLUTION, ENERGY RESOLUTION, AND EFFICIENCY. THIS RESEARCH SHOULD PRODUCE THE HIGHEST RESOLUTION PET MODULAR DETECTOR DESIGN BASED ON FOUR PHOTOMULTIPLIERS.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government