Automated, portable, concurrent, WMD detection system

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$994,832.00
Award Year:
2004
Program:
STTR
Phase:
Phase I
Contract:
1R41AI059138-01A1
Agency Tracking Number:
AI059138
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
CONCURRENT ANALYTICAL, INC.
CONCURRENT ANALYTICAL, INC., BOX 1211, 41-1537 KALANIANAOLE HWY, STE 206, WAIMANALO, HI, 96795
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
CHRISTIAN SCHOEN
(808) 263-6387
CSCHOEN@CONCANA.COM
Business Contact:
(808) 263-6387
Research Institution:
IOWA STATE UNIVERSITY

2207 PEARSON HALL, RM. 15
AMES, IA, 50011

Nonprofit college or university
Abstract
DESCRIPTION (provided by applicant): The overall goal of this project is the development of a fully automated, wireless ethernet capable, near realtime, field deployable immunoassay-based analysis system for the concurrent, ultra low-level detection of biowarfare agents in air or water by using innovations in surface enhanced Raman scattering (SERS) and related supporting materials and hardware. As a proving ground for this concept, this Phase I effort has three major objectives. The first objective is to develop the requisite Raman active labels and sample handling protocols for the simultaneous, low-level detection (approximately 100 biolites) of simulants for Bacillus anthracis (anthrax), Clostridium botulinum (botulism), Yersinia pestis (plague), and Variola major (smallpox). The second objective is to devise a facile approach for sample concentration that will realize equilibration time's prior to readout of less than one minute. The third objective is to reduce the size and power requirements of our current NanoRamanTM I instrument to that of a 1980's cell phone. Thereby, the combined system of Extrinsic Raman Labels (ERLTM) along with the NanoRamanTM I instrument could function as a highly sensitive detection and labeling method that can be applied in a high throughput format by reading multiple biomarkers concurrently at a single biochip detector (sensor) address, and could be utilized for many portable applications. The successful completion of these three objectives will provide the framework upon which in Phase II, a detection system could be made that can detect all of the pathogens listed in Categories A, B and C that are amenable to immunoassay-based analysis, concurrently, with detection levels approaching single biolite and response times of a few minutes, in a compact, low power, portable device.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government