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Next Generation Functional Neuroimaging NGFN Feasibility

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R43MH115885-01A1
Agency Tracking Number: R43MH115885
Amount: $238,517.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: 101
Solicitation Number: PA16-302
Solicitation Year: 2016
Award Year: 2017
Award Start Date (Proposal Award Date): 2017-07-24
Award End Date (Contract End Date): 2019-02-23
Small Business Information
Shoreview, MN 55126-4841
United States
DUNS: 079937344
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 (651) 500-5196
Business Contact
Phone: (651) 500-5194
Research Institution

During the last three decades functional magnetic resonance imaging fMRI using the endogenous blood oxygen
level dependent BOLD effect for contrast has increased our understanding of the healthy and the diseased brain
While fMRI continues to evolve its full potential for neuroscience research and clinical translation will not be
achieved without greatly improved significance at the individual subject patient level as opposed to group
comparison and accuracy repeatability across sessions sites platforms and time Dramatic improvements in fMRI
are required in order to provide robust functional diagnostic information for individual subjects patients and to allow
physicians to take full advantage of emerging invasive and non invasive neuromodulation therapies
The aims of this proposal will accelerate deployment of next generation functional neuroimaging NGFN tools for
greatly improved large scale whole brain recording with significance at the level of an individual subject
dramatically reduced instrumental noise and without the current confounds of auditory vibration and gradient
stimulation This project will therefore have a significant impact on functional imaging and clinical translation and
will with further development potentially lead to direct neural current dipole non invasive recording of neuronal
activity The project will make new tools for greatly improved large scale whole brain activity mapping that doctors and
researchers can use to better understand the human brain

* Information listed above is at the time of submission. *

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