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Advanced virtual simulator for real time ultrasound guided renal biopsy training
Phone: (919) 969-6990
Email: andinet.enqu@kitware.com
Phone: (518) 836-2187
Email: proposals@kitware.com
ABSTRACT
The objectives of the Kidney Precision Medicine Project KPMP project are to create a
kidney tissue atlas define disease subgroups and identify critical cells pathways and targets
for novel therapies by obtaining and evaluating kidney biopsies from participants with acute
kidney injury AKI and chronic kidney disease CKD As part of this effort there is a need for
new technologies that improve the safety of the human kidney biopsy as well as the quality and
diagnostic yield so that the biopsy tissue yields useful research or clinical information
Ultrasound guided kidney biopsy is a critically important tool in the evaluation and management
of renal pathologies The goal of this Phase I SBIR proposal is to develop a virtual simulator to
train clinicians to improve procedural skill competence in real time ultrasound guided renal
biopsy
Although improvements in needle design and ultrasound imaging have been helpful
excellent biopsy technique and skill are essential to consistently obtaining high yield renal
biopsy samples Furthermore poor renal biopsy technique can potentially lead to significant
complications and adverse lethal outcomes The simulator proposed in this project will
accelerate the training of ultrasound guided renal biopsy in a risk free environment ultimately
improving the safety of kidney biopsy and ensuring that the biopsy procedure yields high quality
specimen that can provide useful clinical information
The proposed system will benefit radiologists nephrologists and interventional
radiologists in two ways a Improved three dimensional and dynamic ultrasound imaging
interpretation specific to performing a needle biopsy and b Improved manual dexterity in
needle handling with the aid of tactile feedback This project is a collaboration between Kitware
Inc and Childrenandapos s National Medical Center Kitware is a leader in the creation and support of
state of the art software and technology with more than years of experience in image guided
interventions Childrenandapos s National Medical Center CNMC is an internationally recognized
pediatric hospital with extensive expertise in the clinical management of renal pathologies The
two institutions have already collaborated successfully on several projects including image
guided biopsy projects The aims of the Phase I project are to build the virtual simulator system
and evaluate it by conducting a study with pediatric radiologists nephrologists and
interventional radiologists at CNMC The successful completion of the Phase I work will result in
a proof of concept of our simulator system and lay the groundwork for further system
development and validation in Phase II PROJECT NARRATIVE
The Kidney Precision Medicine Project KPM was initiated to create a kidney tissue atlas
define disease subgroups and identify critical cells pathways and targets for novel therapies by
obtaining kidney biopsies from participants with acute kidney injury and chronic kidney disease
Ultrasound guided renal biopsy is a critically important tool in the evaluation and management
of renal pathologies and it requires competent biopsy technique and skill to consistently obtain
high yield biopsy samples This project aims to develop a virtual simulator to train clinicians to
improve procedural skill competence in real time ultrasound guided renal biopsy
* Information listed above is at the time of submission. *