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STTR Phase II: User-Friendly Spirometer and Mobile App for Self-Management and Home Monitoring of Asthma Patients

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: 1738560
Agency Tracking Number: 1738560
Amount: $500,000.00
Phase: Phase II
Program: STTR
Solicitation Topic Code: BM
Solicitation Number: N/A
Solicitation Year: 2015
Award Year: 2017
Award Start Date (Proposal Award Date): 2017-09-15
Award End Date (Contract End Date): 2019-08-31
Small Business Information
175 Bluxome Street Unit 234
San Francisco, CA 94107-1552
United States
DUNS: 079168163
HUBZone Owned: No
Woman Owned: Yes
Socially and Economically Disadvantaged: No
Principal Investigator
 Charvi Shetty
 (415) 320-0690
Business Contact
 Charvi Shetty
Phone: (415) 320-0690
Research Institution
 University of California-San Francisco
 Ngoc Ly
1855 Folsom St Ste 425
San Francisco, CA 94103-4249
United States

 Nonprofit College or University

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project is the development of a user-friendly asthma management solution. The asthma management tool consists of a portable medical device and mobile app combination that measures lung function with the consistency and accuracy of a trained lab technician, displaying current asthma status, and providing health insights to act upon. During the 2-year duration of this proposal, the applicant will further develop a machine-learning algorithm that obtains the same level of consistency and accuracy as if a trained lab technician were coaching and correcting the asthmatic patient on proper usage. Steps will be taken to establish the efficacy of such technology through verification of classification by pulmonologists. In order to engage users to continue using the product over several months, gamification elements will be implemented into the mobile app. By expanding on the machine-model through a longitudinal study, earlier detection of asthma exacerbations may be identified. Early detection leads to improved self-management as measured by the reduction of severe asthma attacks, the use of systemic corticosteroids, hospitalizations, emergency department or urgent care visits related to asthma. The proposed project aims to develop an asthma management tool that provides parents a simple way to reliably monitor their child's lung health, eliminating the guesswork associated with relying on symptoms alone. The rate of asthma continues to rise, with an increasing amount of healthcare utilization among asthmatic individuals. Effective technologies for proper management remain trapped within the hospital due to high costs and requirement of a skilled lab technician for proper measurement collection. This proposal aims to develop an algorithm alongside UCSF pediatric pulmonologists to gain consistent and accurate spirometry measurements, so that only proper measurements are acted upon. Our machine-learning algorithm will determine the cause of failure and prompt the user on corrective action to achieve a good quality measurement on a subsequent effort. By the end of this proposal period, the applicant will have a mobile app algorithm that is able to achieve the consistency of a trained lab technician, provide effective corrective feedback, engage users over the span of months for consistent lung monitoring, and potentially predict the onset of an asthma attack.

* Information listed above is at the time of submission. *

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