THE DETERMINATION OF ORGANIC ACIDS IN FERMENTATION BROTHS BY AN ELECTROCHEMICAL SENSOR

Award Information
Agency: Department of Energy
Branch: N/A
Contract: N/A
Agency Tracking Number: 340
Amount: $482,770.00
Phase: Phase II
Program: SBIR
Awards Year: 1984
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Covalent Associates Inc.
52 Dragon Court, Saxonville Station, Woburn, MA, 01801
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Dr. Victor R. Koch
 () -
Business Contact
Phone: () -
Research Institution
N/A
Abstract
THE PRODUCTION OF COMMERCIALLY IMPORTANT CHEMICAL FEEDSTOCKSBY MICROBIAL FERMENTATION IS HINDERED BY THE INABILITY TO MONITOR THE ONSET OF PRODUCT AND/OR BYPRODUCT FORMATION. SINCE MANY MICROORGANISMS UTILIZING GLUCOSE AS A SUBSTRATE GENERATE CARBOXYLIC ACIDS, AN "IN SITU" ORGANIC ACID SENSOR WOULD BE A VALUABLE ADDITION TO ANY BIOREACTOR DESIGN. THROUGH THE USE OF A MULTIPHASE POTENTIODYNAMIC WAVEFORM AND A CHEMICALLY MODIFIED ELECTRODE SURFACE, ACETIC, LACTIC,AND PYRUVIC ACIDS WILL BE DETECTED AND QUANTIFIED IN A BULK FERMENTATION BROTH. THESE DATA WILL THEN BE CORRELATED WITHGAS-LIQUID CHROMATOGRAPHY ANALYSIS RUN ON THE SAME FERMENTATION BROTH.

* information listed above is at the time of submission.

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