SEACHANGE PHARMACEUTICALS, INC.
SAN JOSE, CA, 95128-2532
|# of Employees:||2|
|Socially and Economically Disadvantaged:||N|
DESCRIPTION (provided by applicant): Goals: The goal is to expand the known pharmacological relationships among arrestin and G protein biased ligands. Starting with the Gi-coupled dopamine D2 rec ...SBIRPhase I2013Department of Health and Human Services
DESCRIPTION (provided by applicant): Bioactive small molecules can act on multiple targets, and these off-target activities underlie many of the adverse reactions from which drugs suffer. The motivati ...SBIRPhase II2013Department of Health and Human Services
DESCRIPTION (provided by applicant): Goals: The goal is to develop a computational system to predict the targets toward which small molecules are biased. The tool will optimize biased libraries, prior ...SBIRPhase I2011Department of Health and Human Services
DESCRIPTION (provided by applicant): Three ideas motivate this project. First, bioactive small molecules often act on multiple targets- sometimes this polypharmacology is key to their efficacy, some ...SBIRPhase I2010Department of Health and Human Services