Not Available

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N43CO201000136
Agency Tracking Number: N43CO201000136
Amount: $200,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2010
Solitcitation Year: 2010
Solitcitation Topic Code: NCI
Solitcitation Number: PHS2010-1
Small Business Information
ORANOXIS, INC.
10366 ROSELLE ST, SAN DIEGO, CA, 92121-
Duns: 843649398
Hubzone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Daniel Wang
Business Contact
Phone: (858) 692-2943
Research Institution
N/A
Abstract
Different patients react very differently to chemotherapeutic cancer drugs, and are variably susceptible to drug side effects. Many patients are therefore currently not receiving adequate levels of those drugs. A personalized monitoring of toxic drug metabolites would greatly aid physicians to accurately personalize drug dosage. We propose to develop a rapid oral fluid test of a panel of small drug metabolites for personalized diagnostic monitoring during treatment. We will utilize our patented design for a "discontinuous chromatographic capillary flow solid phase assay", The test can be designed both for home self-monitoring by the patient (over-the-counter device) and for use by physicians in clinics (point-of-care). The key features include: (i), highly sensitive detection of small molecule drug metabolites

* information listed above is at the time of submission.

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