Early Detection of Mild Traumatic Brain Injury

Award Information
Agency:
Department of Defense
Branch
Office of the Secretary of Defense
Amount:
$99,999.00
Award Year:
2010
Program:
SBIR
Phase:
Phase I
Contract:
W81XWH-10-C-0188
Award Id:
96850
Agency Tracking Number:
O093-H08-3186
Solicitation Year:
n/a
Solicitation Topic Code:
OSD 09-H08
Solicitation Number:
n/a
Small Business Information
246 Sylvan RD, Suite C, Bangor, ME, 04401
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
MarieHayes
Chief Scientific Officer
(207) 973-4963
mjhayes@emh.org
Business Contact:
MarieHayes
Chief Scientific Officer
(207) 973-4963
mjhayes@emh.org
Research Institute:
n/a
Abstract
Early detection of positive mild traumatic brain injury (mTBI) status is difficult in the post-trauma period and efficient, noninvasive screening methods are needed. Brain injury from trauma and other neurological conditions frequently escapes detection using current imaging technology such as magnetic resonance (MRI) and computer-assisted tomography (CAT). mTBI is associated with cognitive impairment in attention, learning and information processing is correlated with sleep disorder and accumulating sleep deprivation. This proposal aims to use the PI's prior sleep and brain injury discoveries in humans to develop a prototype device that can detect sleep anomalies for the diagnosis of both mTBI presence and severity. An interdisciplinary approach will be used for prototype development using cutting edge engineering science innovation in sensor fabrication, wireless signal processing and software development. The prototype device will use proprietary sleep algorithms associated with brain injury and compare results to neurocognitive outcome measures. The Phase II plan is to test this simple, noninvasive device in a home-based setting. Recent mTBI military outpatients will be compared to a sample of military patients without brain injury in overnight tests using the device. Commercialization plans include device development for early diagnosis of mTBI and future applications to other brain injury etiologies.

* information listed above is at the time of submission.

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