CREATIVE BIOMOLECULES, INC.

Company Information

Company Name
CREATIVE BIOMOLECULES, INC.
Address
45 SOUTH STREET
Hopkinton, MA, 01748
Phone
n/a
URL
n/a
DUNS
n/a
Number of Employees
n/a
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N

Award Totals

PROGRAM/PHASE
AWARD AMOUNT ($)
NUMBER OF AWARDS
SBIR Phase I
$549,637.00
9
SBIR Phase II
$760,000.00
2

Award List

  1. ENGINEERING OF ANTIBODY BINDING SITES TO TUMOR ANTIGENS

    Amount: $260,000.00

    IN THIS RESEARCH, PROTEIN ENGINEERING IS BEING UTILIZED TO GENERATE THE MINIMAL COMBINING SITE OF ANTIBODIES, THE SO-CALLED FV, WHICH COMPRISES VH AND VL DOMAINS. IN PHASE I WE SYNTHESIZED GENES CODIN ...

    SBIR Phase II 1987 Department of Health and Human Services
  2. CARTILAGE MATRIX PROTECTION BY FORMS OF TIMP

    Amount: $50,000.00

    THE GOAL OF THIS RESEARCH IS TO EVALUATE THE ROLE OF METALLOPROTEASE INHIBITORS IN CONTROLLING THE PATHOLOGICAL PROGRESSION OF JOINT DISEASES. IN PHASE I, IT IS PLANNED TOCHARACTERIZE THE ABILITY OF F ...

    SBIR Phase I 1989 Department of Health and Human Services
  3. INTERACTIVE EFFECTS OF GROWTH FACTORS ON CARTILAGE

    Amount: $50,000.00

    THE GOAL OF THIS RESEARCH IS TO ELUCIDATE THE ACTION OF SELECTED PEPTIDE GROWTH FACTORS ON ADULT ARTICULAR CARTILAGE. BOVINE ARTICULAR CARTILAGE IN SERUM-FREE ORGAN CULTURE WILL BE USED TO EVALUATE TH ...

    SBIR Phase I 1989 Department of Health and Human Services
  4. PDGF-AA-DIMER STRUCTURE AND ATHEROSCLEROSIS DRUG DESIGN

    Amount: $50,000.00

    THIS PROJECT WILL DEVELOP THE BASIS FOR STRUCTURE ANALYSIS OF PDGF-AA IN PHASE I, LEADING TO ITS 3-D STRUCTURE DETERMINATION IN PHASE II. THE ULTIMATE GOAL IS TO USE THE 3-D STRUCTURE OF PDGF TO DEVEL ...

    SBIR Phase I 1990 Department of Health and Human Services
  5. HUMANIZED ANTITUMOR BINDING SITES: FRAMEWORK ENGINEERING

    Amount: $50,000.00

    ANTIBODY VARIABLE (V) REGIONS EACH COMPRISE 3 COMPLEMENTARY DETERMINING REGIONS (CDRS) THAT FORM THE ANTIGEN BINDING SITE AND 4 FRAMEWORK REGIONS (FRS) THAT FORM THE SCAFFOLD SUPPORTING THE BINDING SI ...

    SBIR Phase I 1991 Department of Health and Human Services
  6. GROWTH FACTOR REGENERATION OF PERIODONTAL TISSUE

    Amount: $500,000.00

    THE GOAL OF THIS STUDY IS THE REGENERATION OF SOFT AND HARD TISSUE LOST DUE TO PERIODONTAL DISEASE. THIS WILL BE TESTED IN PHASE I BY: (1) FORMULATION OF BIOSYNTHETIC HUMAN GROWTH FACTORS IN A VARIETY ...

    SBIR Phase II 1993 Department of Health and Human Services
  7. SINGLE-CHAIN FV-PEPTIDE FUSION INHIBITOR OF FIBRIN CLOTS

    Amount: $50,000.00

    GIVEN THE MAJOR IMPORTANCE OF CARDIOVASCULAR DRUGS TO PUBLIC HEALTH IN THIS COUNTRY, IT IS REMARKABLE THAT THERE ARE STILL NO CLINICALLY EFFECTIVE AGENTS THAT ACT DIRECTLY ON THE FIBRIN DURING THE CLO ...

    SBIR Phase I 1991 Department of Health and Human Services
  8. OP-1 3D STRUCTURE USED IN DRUG DESIGN FOR BONE DISORDERS

    Amount: $99,943.00

    N/A

    SBIR Phase I 1997 Department of Health and Human Services
  9. OP-1 TREATMENT FOR PARKINSONS DISEASE

    Amount: $100,000.00

    N/A

    SBIR Phase I 1998 Department of Health and Human Services
  10. GROWTH FACTOR REGENERATION OF PERIODONTAL TISSUE

    Amount: $49,694.00

    N/A

    SBIR Phase I 1991 Department of Health and Human Services

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