DEVELOPMENT OF A FIBRIN SEALANT DELIVERY METHOD

Award Information
Agency:
Department of Health and Human Services
Branch:
N/A
Amount:
$500,000.00
Award Year:
1993
Program:
SBIR
Phase:
Phase II
Contract:
N/A
Agency Tracking Number:
16703
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Cryolife, Inc.
2211 New Market Parkway, Suite, 14, Marietta, GA, 30067
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
N/A
Principal Investigator
 Morse, Brenda S
 Principal Investigator
 (404) 952-1660
Business Contact
 1 R43 HL46096-01
Phone: () -
Research Institution
N/A
Abstract
FIBRIN SEALANT HAS MANY APPLICATIONS IN SURGERY. MIXING AND DELIVERY OF THE MAJOR COMPONENTS, FIBRINOGEN AND THROMBIN, IS CURRENTLY ACHIEVED USING TWO SYRINGES OR SPRAY CONTAINERS DISPENSED ALTERNATELY OR SIMULTANEOUSLY TO DELIVER FIBRIN SEALANT ONTO THE WOUND SITE. THESE SYSTEMS OF DELIVERY ARE UNSATISFACTORY DUE TO INADEQUATE MIXING OF THE SOLUTIONS. A CHAMBER CAN BE ATTACHED TO THE SYRINGES TO FACILITATE MIXING, BUT CLOGGING OCCURS AND FREQUENT REPLACEMENT OF THE NEEDLE, CHAMBER, AND SYRINGES IS REQUIRED. THE OBJECTIVE OF THIS STUDY IS TO DEVELOP AND EVALUATE A UNIQUE METHOD FOR THE MIXING AND DELIVERY OF FIBRIN SEALANT IN A SINGLE SYRINGE OR CONTAINER SYSTEM.

* information listed above is at the time of submission.

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