Xenogeneic Arterial Bypass Graft

Award Information
Agency:
Department of Health and Human Services
Branch:
N/A
Amount:
$73,360.00
Award Year:
1995
Program:
SBIR
Phase:
Phase I
Contract:
1 R43 HL53192-01,
Agency Tracking Number:
29497
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Cryolife, Inc.
2211 New Market Parkway, Suite, Marietta, GA, 30067
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
N/A
Principal Investigator
 Steven Goldstein
 () -
Business Contact
Phone: () -
Research Institution
N/A
Abstract
Although the autogenous saphenous vein is the vessel typically utilized in arterial bypass procedurarise in which it is not possible to use this vein, demanding an alternative method. The investigatofeasibility study in canine subjects to determine whether an immunologically modified xenogeneic vesendothelium can serve as a replacement of the autogenous saphenous vein. The investigators intend tothe tissue modification technique, and seek to optimize endothelial cell seeding. The final object oassess in vivo the biocompatibility of the implant, as well as its overall effectiveness as a graft.

* information listed above is at the time of submission.

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