THE PURPOSE OF THIS PROJECT IS TO ESTABLISH THE FEASIBILITY FOR A NEW CONCEPT OF MEASURING SWEAT AND URINE OSMOLARITY.

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$43,600.00
Award Year:
1984
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Agency Tracking Number:
1369
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Daniel Kerschensteiner Assoc.
76-q Farm Road, Hillsborough, NJ, 08876
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
D. KERSCHENSTEINER
OWNER
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
THE PURPOSE OF THIS PROJECT IS TO ESTABLISH THE FEASIBILITY FOR A NEW CONCEPT OF MEASURING SWEAT AND URINE OSMOLARITY. THIS MEASUREMENT IS VALUABLE AS AN AID IN IDENTIFYING CYSTIC FIBROSIS IN INFANTS AND ALSO FOR MONITORING SALT INTAKE IN HYPERTENSIVE INDIVIDUALS. BOTH OF THESE TESTS ARE COMMERCIALLY DESIRABLE. THIS TEST IS BASED ON A PROVEN BUT PROPRIETARY METHOD THAT EMPLOYS AN OSMOLARITY-SENSITIVE REACTANT AND A SPECIAL DYE WHICH CHANGES COLOR IN RESPONSE TO SMALL CHANGES IN IONIC STRENGTH. A QUALITATIVE AND A SEMI-QUANTITATIVE TEST ARE ENVISIONED FOR PHASE II-- AS SIMPLE AND AS EASILY READ AS CURRENTLY AVAILABLE PH DIP STICK TESTS. PHASE I OF THE PROPOSED PROJECT IS A SURVEY AND AN IDENTIFICATION OF THE BEST COMBINATION OF REACTANT AND DYE; THEN, TESTING OF THEIR PERFORMANCE UNDER CONTROLLED CONDITIONS USING THE NORMAL LEVELS OF THE ELECTROLYTES FOUND IN SWEAT AND URINE WILL BE PERFORMED. ONCE A WORKING LIQUID FORMULATION IS DISCOVERED, THE REAGENTS WILL BE DRIED IN A FILM OR ON PAPER FOR POTENTIAL USE IN A DIP STICK OR SLIDE-TYPE ARRANGEMENT.

* information listed above is at the time of submission.

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