TOPIC 360: A SIMPLE END-TO-END SYSTEM FOR SERIAL CELL SORTING AND MANIPULATION USING A SINGLE CONTAINER

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 261201700051C-1-0-0
Agency Tracking Number: N43CA170051
Amount: $50,000.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: NCI
Solicitation Number: N/A
Timeline
Solicitation Year: 2016
Award Year: 2018
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
5820 Oberline Dr., #104, SAN DIEGO, CA, 92121
DUNS: 078518178
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Guixin Shi
 (858) 886-6353
 guixinshi@gmail.com
Business Contact
 Guixin Shi
Phone: (858) 886-6353
Email: guixinshi@gmail.com
Research Institution
N/A
Abstract
Chemotherapy may control but rarely cure metastatic cancers. Remarkably, modern immunotherapies, including cell-based therapies, have cured metastatic melanomas and other types of cancers. A major challenge for all cell therapies in general is the need to develop cost-effective and efficient manufacturing and delivery capabilities. We have recently established an innovative cell isolation technology by applying targeted microbubbles, which have a number of interesting properties that are ideal for bulk cell isolation. Here we propose a simple and cost-efficient system to enrich cells of interest that require multiple markers to identify by integrating these features. When this project is successful, a closed automated system using only a single container will be developed and manufactured for cell isolation, expansion and manipulation.

* Information listed above is at the time of submission. *

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