CELLS

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: N/A
Agency Tracking Number: 2594
Amount: $39,000.00
Phase: Phase I
Program: SBIR
Awards Year: 1985
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Advanced Genetic Sciences Inc
6701 San Pablo Ave, Oakland, CA, 94608
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 JOHN BEDBROOK PHD
 VICE PRES/DIR OF RESEARCH
 (415) 547-2315
Business Contact
Phone: () -
Research Institution
N/A
Abstract
A RATE LIMITING FACTOR TO USEFUL GENETIC ENGINEERING IN PLANTS IS THE ISOLATION OF PLANT GENES WHICH CONFER AGRONOMICALLY IMPORTANT PROPERTIES TO CROP PLANTS. TRADITIONAL GENE ISOLATION PROCEDURES WHICH ARE BASED ON A KNOWLEDGE OF THE GENE PRODUCT ARE OF LIMITED USE BECAUSE THEBIOCHEMICAL BASIS OF IMPORTANT PROPERTIES SUCH AS DISEASE RESISTANCE, FERTILITY AND YIELD ARE UNKNOWN. THIS PROPOSAL DESCRIBES THE DEVELOPMENT OF A METHOD FOR THE DIRECT SELECTION OF IMPORTANT GENES IN PLANT CELLS. IT IS A SYSTEMINVOLVING DIRECT "SHOTGUN" CLONING OF PLANT DNA INTO PLANT CELLS COUPLED WITH THE RESCUE OF GENES CONFERRING A PARTICULAR SELECTABLE PHENOTYPE ON THOSE PLANT CELLS. THIS TECHNOLOGY WILL ENABLE THE DIRECT SELECTION AND ISOLATION OFPLANT GENES WHICH CONFER RESISTANCE TO NATURAL TOXINS AND TOXIC CHEMICALS.

* information listed above is at the time of submission.

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