A Low-cost, Intravascular Ultrasound Transducer System for Measuring Blood Flow

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$125,182.00
Award Year:
2009
Program:
SBIR
Phase:
Phase I
Contract:
1R43HL095195-01
Award Id:
93940
Agency Tracking Number:
HL095195
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
DVX, LLC, 31 AIRPARK RD, Princeton, NJ, 08540
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
139114487
Principal Investigator:
DAVIDVILKOMERSON
(609) 924-3590
DV1DVX@COMCAST.NET
Business Contact:
DAVIDVILKOMERSON
() -
dv1dvx@comcast.net
Research Institute:
n/a
Abstract
DESCRIPTION (provided by applicant): Over a million minimally invasive procedures to preserve blood flow - angioplasties, stent placements, thrombectomies - are performed each year in the United States. The goal of this program is to provide means of measu ring blood flow in these vessels during and after these procedures, something now not possible. We have developed a new blood-flow measuring component that can be integrated into minimally invasive interventional devices. During the procedure, it provides quantitative feedback to the operator on success in restoring blood flow; after the procedure, it can be remain as an indwelling lead to measure blood flow post-operatively. Its low power requirement also makes it suitable for long-term implantable use -- a small implanted unit, like a pacemaker, can monitor flow and wirelessly communicate an alert when declining blood flow demands intervention. This intravascular blood-flow measuring device is a newly developed, unique ultrasound transducer system. The des ign utilizes the principle of diffraction-grating transducers, which have been proven to measure blood flow accurately. A special configuration has been invented to make the transducer suitable for intravascular use: the electrodes on this transducer are w ound around a rod, in helices, like a screw thread. This design has several advantages: it allows piezoplastics to be used at high frequencies, leading to low power requirements; use of piezoplastics makes a light, flexible device possible; it is easy to c onnect to; and, importantly, it is inexpensive to fabricate. Phase I of this project is to prove the concept by fabricating these transducers and demonstrating their capabilities in test phantoms, followed by placing one by minimally invasive means in a li ving animal and demonstrating successful blood flow measurement. PUBLIC HEALTH RELEVANCE: The goal of this program is to develop an intravascular device to measure blood flow during and after operations that improve or restore blood flow. By monitoring blo od flow and alerting caregivers to a problem, it can prevent the serious consequences of too little flow of blood.

* information listed above is at the time of submission.

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