HIGH SENSITIVITY URANIUM BIOASSAY

Award Information
Agency: Nuclear Regulatory Commission
Branch: N/A
Contract: N/A
Agency Tracking Number: 18845
Amount: $50,000.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Timeline
Solicitation Year: N/A
Award Year: 1992
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
335 Paint Branch Drive, College Park, MD, 20742
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 () -
Business Contact
Phone: () -
Research Institution
N/A
Abstract
DETERMINATION OF URANIUM IN THE URINE OF WORKERS IS REQUIRED BY THE NRC AT NUCLEAR FACILITIES. EXTREMELY LOW CONCENTRATIONS OF URANIUM, ESPECIALLY IN SMALL SAMPLES, ARE DIFFICULT TO MEASURE USING EXISTING TECHNOLOGY. FUTURE NRC PLANS TO CHARACTERIZE BIOAVAILABLE URANIUM FRACTIONS COMPRISING THE URANIUM BODY BURDEN WILL REQUIRE EVEN HIGHER SENSITIVITIES. HIGH SENSITIVITY TECHNOLOGY DEVELOPED FOR URANIUM IS POTENTIALLY AMENABLE TO NUMEROUS BIOASSAY, ENVIRONMENTAL, GEOLOGICAL, AND SEMICONDUCTOR MATERIALS APPLICATIONS. RECENT DEVELOPMENTS IN AUTOIONIZATION-MEDIATED LASER PHOTOIONIZATION (A-MLAP) MASS SPECTROMETRY SUGGEST THAT NEW LEVELS OF SENSITIVITY AND SELECTIVITY MAY BE ATTAINABLE TO MEET EVOLVING NEEDS FOR IRANIUM (BIO)ASSSY. THE PURPOSE OF THIS PROJECT IS TO EXPLORE THE FEASIBILITY OF A-MLAP FOR URANIUM ANALYSIS. WE PROPOSE TO EVALUATE AUTOIONIZATION PATHWAYS, ATOMIZATION EFFICIENCY, A PILOT URANIUM IN URINE QUANTIFICATION STUDY AND EXTRAPOLATION OF THE METHODOLOGY TO CONTINUOUS WAVE SOLID- STATE LASER SYSTEMS. A SUCCESSFUL COMPLETION OF THIS PROJECT WOULD PERMIT IMPLEMENTATION OF THE TECHNOLOGY IN A HIGH SENSITIVITY ANALYSIS SYSTEM IN PHASE II AND BEYOND.

* Information listed above is at the time of submission. *

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government