INSIGHT GENETICS, INC.
Kinase inhibitors such as Gleevec and Tarceva have markedly improved cancer therapy. Essential to the use of such inhibitors are companion diagnostics enabling determination of the mutational status o ...SBIR Phase I 2010 Department of Health and Human Services
Constitutively activated forms of ALK caused by genetic aberrations have been shown to cause an expanding variety of human cancers. The FDA recently approved the Pfizer drug Xalkori (crizotinib) to t ...SBIR Phase II 2012 Department of Health and Human Services
Lung cancer is the main cause of cancer mortality worldwide with 80% non-small cell lung cancer (NSCLC) in type and mainly driven by three mutually exclusive oncogenes, EGFR, KRAS and ALK (collectivel ...SBIR Phase I 2012 Department of Health and Human Services
Not AvailableSBIR Phase II 2013 Department of Health and Human Services