Human Performance Optimization

Award Information
Agency: Department of Defense
Branch: Special Operations Command
Contract: H9222218P0036
Agency Tracking Number: S17C-001-0016
Amount: $149,904.00
Phase: Phase I
Program: STTR
Awards Year: 2018
Solicitation Year: 2017
Solicitation Topic Code: SOCOM17C-001
Solicitation Number: 2017.0
Small Business Information
235 freeman apt 3, brookline, MA, 02116-Array
DUNS: 080085661
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Noah Davidsohn
 (516) 473-1287
 noah@rejuvenatebio.com
Business Contact
 Daniel Oliver
Phone: (916) 396-3714
Email: dan@rejuvenatebio.com
Research Institution
 Jackson Laboratory
 Michael Walden
 600 Main St
Array
bar harbor, ME, 04609
 (207) 288-1461
 Domestic nonprofit research organization
Abstract
Special Operations Forces (SOF) are an integral aspect of the US military. SOF operators are among the most elite and highly qualified individuals in the U.S. military. As such, extraordinary physical and mental demands are placed upon them to excel in extreme environments for extended periods of time. This unrelenting cycle of combat deployments and intense pre-deployment training shortens the functional life of operators, a highly undesirable outcome. Rejuvenate Bio developed a gene therapy platform that identified genes that can increase the stress-resistance, health and lifespan of mice as well as mitigate three different age-related diseases (heart failure, diabetes and obesity). We believe that these novel gene therapies will also enhance performance due to their modulations of stress responses and metabolic energy pathways. As a first step toward developing therapies for humans, we propose to measure the effect of these gene therapies on endurance, speed of recovery, and resistance to muscle damage. Completion of this Phase I study will enable us to begin Phase II testing of these therapies ability to enhance performance in a large animal model (canines). Using aging as a model to discover performance enhancing genes will allow for increased performance now and far into the future.

* Information listed above is at the time of submission. *

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government