Heat Stable Nanoparticle Amplified Immunoassays

Award Information
Agency:
Department of Defense
Branch
Defense Advanced Research Projects Agency
Amount:
$98,972.00
Award Year:
2007
Program:
SBIR
Phase:
Phase I
Contract:
W31P4Q-08-C-0030
Award Id:
81256
Agency Tracking Number:
07SB2-0073
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
111 Downey Street, Norwood, MA, 02062
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
076603836
Principal Investigator:
Michael Wilson
Senior Scientist
(781) 769-9450
mwilson@eiclabs.com
Business Contact:
R. Rauh
President
(781) 769-9450
drauh@eiclabs.com
Research Institute:
n/a
Abstract
The theater of operation for DoD immunoassays typically requires them to be sensitive, stable at temperatures up to 35 oC for up to two years, and be low power or power-free. Although enzyme-based assays are very sensitive, enzymes are usually unstable under such storage conditions. We propose a new photocatalytic nanoparticle-based immunoassay method that provides the amplification associated with enzyme-based assays but without the instability problems associated with enzymes. The method can be readily adapted to lateral flow immunoassays, which provide convenient testing in the field, but often suffer from poor sensitivity. In addition, the technology can also be used in biosensors and lab-based immunoassays.

* information listed above is at the time of submission.

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