Distributed Statistical Source Localization

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$98,735.00
Award Year:
1995
Program:
SBIR
Phase:
Phase I
Contract:
1 R43 NS34598-01,
Award Id:
29647
Agency Tracking Number:
29647
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
1811 Garden Avenue, Suite 104, Eugene, OR, 97403
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
K Eriksen
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
Advances in dense sensor array measurement of brain electrical activity promise new insights into tthe human brain. This project develops Sourcerer(R), an innovative software package for distributedanalysis of Electroencephalographic (BEG) and Event-Related Potential (BRP) data. Whereas conventionmodels approximate gross regions of the brain, Sourcerer will characterize distributed source configareas of cortex. Drawing from other Electrical Geodesics Incorporated (EGI) software, anatomic constmagnetic resonance imaging (MRI) will be available for the source modeling. Three optimization technevaluated in Phase I: polytope algorithm, simulated annealing, and Bayesian estimation. As its namerequires a skilled user for accurate results. Like any other electrical source analysis software, itneural sources rather than exact measurements. Unlike any existing approach, however, Sourcerer willcheck on its results: a Bayesian analysis of the statistical reliability of each source solution. Aerrors due to model misspecification and finite sampling of head electric fields will guide this vallocalization solutions and interpretations will be guided by the high spatial resolution yielded byLaplacian) estimates.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government