Low-Cost Microfluidic System for Detection of CTC's

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N43CO201000066
Agency Tracking Number: N43CO201000066
Amount: $199,517.00
Phase: Phase I
Program: SBIR
Awards Year: 2010
Solicitation Year: 2010
Solicitation Topic Code: NCI
Solicitation Number: PHS2010-1
Small Business Information
Emerging Technology Center, 340 E PARKER, LSU CAMPUS, BATON ROUGE, LA, 70803
DUNS: 808078765
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Mateusz Hupert
 (225) 756-8437
 david@biofluidica.com
Business Contact
Phone: (225) 756-8437
Email: david@biofluidica.com
Research Institution
N/A
Abstract
While the clinical utility of circulating tumor cells (CTCs) for the management of many different types of cancers are being realized, the challenge in selecting them from peripheral blood and enumerating them is daunting due to the exceedingly high numbers of spectator cells (erythrocytes and leukocytes) and the low abundance of the CTCs (< I0/7.5 ml of whole blood). The goal of this project is to fabricate and evaluate the performance of an exciting new technology for the analysis of CTCs. The technology consists of a fluidic cartridge made from conventional plastics, such as Plexiglas, through micro-replication that can select CTCs from blood in under 20 min with recoveries >go%. The cartridge will also enumerate the selected CTCs using a non-labeling process that requires no optical equipment

* Information listed above is at the time of submission. *

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