SBIR Phase I:Phage detectors for bacterial pathogens

Award Information
Agency:
National Science Foundation
Branch
n/a
Amount:
$149,974.00
Award Year:
2010
Program:
SBIR
Phase:
Phase I
Contract:
0945976
Agency Tracking Number:
0945976
Solicitation Year:
n/a
Solicitation Topic Code:
A5
Solicitation Number:
n/a
Small Business Information
Alpha Universe
1202 Ann Street, Madison, WI, 53713
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
144579641
Principal Investigator:
Alexey Zdanovsky
PhD
(608) 661-0861
alexeyzd@tds.net
Business Contact:
Alexey Zdanovsky
PhD
(608) 661-0861
alexeyzd@tds.net
Research Institution:
n/a
Abstract
This Small Business Innovation Research (SBIR) Phase I project has a goal of creating a system that, while being inexpensive and simple to use, will be able to analyze samples for the presence of a live pathogenic bacteria and determine their species, as well as sensitivities to antibiotics within just a few hours. As detectors, this system will utilize modified bacteriophages. To prove the concept, it is proposed to create the first detector of the system targeted at Campylobacters, which are emerging as one of the most significant causes of human gastrointestinal infections worldwide. The broader impacts of this research are expected in the biodefense area and medicine where a flexible detection system will allow simultaneous multiparameter monitoring of the environment or food and water supplies for their safety, as well as enable physicians to choose the appropriate antibiotic at very early stages of bacterial infection, thus increasing the efficiency of treatment and reducing the spread of antibiotic-resistant bacteria.

* information listed above is at the time of submission.

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