Topic 343 - MindCap: Monitoring for Cognitive Impairment and Dyfunction in Cancer Patients

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 75N91018C00038-0-0-0
Agency Tracking Number: N44CA180038
Amount: $1,499,993.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: NCI
Solicitation Number: N/A
Solicitation Year: 2017
Award Year: 2018
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
15400 Calhoun Dr., ROCKVILLE, MD, 20855
DUNS: 161911532
HUBZone Owned: N
Woman Owned: Y
Socially and Economically Disadvantaged: N
Principal Investigator
 Lisa Holt
 (301) 294-5212
Business Contact
 Lisa Holt
Phone: (301) 294-5212
Research Institution
Persistent cognitive impairment is a frequent complaint of cancer patients undergoing chemotherapy. The current tests used to assess cognitive function are not sensitive enough to capture the degree of decline associated with cancer-related cognitive impairment (CRCI). In addition, they require professional administration and are subject to practice effects so they cannot practically be used for the longitudinal studies needed to advance our understanding of CRCI. The innovative MindCap solution proposed by Intelligent Automation, Inc. (IAI) and its partner NTI, Inc. will enable self-assessment with the following features: - Cognitive tests quantitatively selected to target the cognitive domains at risk for decline in the cancer population. - Sensitive tests that can detect the less severe, but still debilitating cognitive impairments experienced by patients. - Accessible tests that can be taken outside of a clinical setting, on a personal mobile device, with no provider intervention. - Brief tests, requiring no more than 10 minutes per session, 2-3 times per week. - Repeatable tests that are intended to be practiced, therefore enabling longitudinal monitoring. - Adaptive testing utilizing personal baselines (achieved through practice) to detect decline (vs. norm-based approaches). - Patient logging of cognitive complaints and situational factors to correlate with quantitative data. - A web portal that allows researchers and clinicians to monitor patient performance.

* Information listed above is at the time of submission. *

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