Non-invasive assay to discriminate between mild-Traumatic Brain Injury (TBI) and Post traumatic Stress Disorder (PTSD)

Award Information
Agency:
Department of Defense
Branch
Defense Advanced Research Projects Agency
Amount:
$99,885.00
Award Year:
2009
Program:
STTR
Phase:
Phase I
Contract:
W81XWH-09-C-0150
Award Id:
90067
Agency Tracking Number:
A09A-025-0210
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
P.O. Box 8175, Charlottesville, VA, 22906
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
942413162
Principal Investigator:
MartinBaruch
Chief Scientist
(434) 296-7000
mcbaruch@comcast.net
Business Contact:
DavidGerdt
President
(434) 296-7000
davidetc@firstva.com
Research Institute:
University of Virginia
Sarah White
P.O. Box 400195
Charlottesville, VA, VA, 22901
(434) 924-8426
Nonprofit college or university
Abstract
The objective of this project is the development of an assessment system that will be able to determine the likelihood of a warrior having suffered a mild traumatic brain injury (mTBI). The basis of the determination will be a computerized assessment of the functioning of the II, III, IV, VI, and VIII cranial nerves. This set of nerves provides the opportunity to obtain a sensitive and quantitative evaluation of two critical physiological control systems, eye movement and postural balance, that are, because of their high degree of sophistication, very sensitive to cerebral injury. In conjunction with mTBI experts part of the aim of the Phase I effort will be to evaluate and down-select different eye movement tracking and postural control assessment technologies and neurological testing criteria. In addition, control algorithms based on established machine learning approaches will be designed to enable the system to integrate inputs from the multiple sensor systems and to make categorical decisions. Comprehensive plans for Phase II for the construction of a prototype system and its testing in a population of injured warriors large enough to yield statistically significant results to support the validity of the neurological testing criteria will be laid out.

* information listed above is at the time of submission.

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