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Development of a secure, cloud-based platform to improve record linkage & cross-agency collaboration for the public sector: using deep learning & scalable data integrations to combat the opioid crisis

Award Information
Agency: Department of Health and Human Services
Branch: Centers for Disease Control and Prevention
Contract: 1R43CE002937-01
Agency Tracking Number: R43CE002937
Amount: $225,000.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: NCIPC
Solicitation Number: PA17-302
Solicitation Year: 2017
Award Year: 2018
Award Start Date (Proposal Award Date): 2018-09-30
Award End Date (Contract End Date): 2019-03-31
Small Business Information
Redwood City, CA 94061-3269
United States
DUNS: 080970128
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 (415) 960-7898
Business Contact
Phone: (602) 463-7555
Research Institution

Project Summary AbstractThis SBIR Phase I proposal aims to fund research and development for a newmultitenant secure cloud based
platform specifically tailored to provide local governmental agencies with tools to share datasets and link them
accuratelyat high quality and low costThe OpenLattice platform will focus on reducing drug overdoses and
making drug treatment less fracturedIndividual level datasets linked across medical providers and law
enforcement can support analyses of prescribing pathways and treatment trajectories that precede opioid
overdoseentry into treatmentdisruptionand recoveryHoweverlinking data at the individual level has
proven to be a difficult and resource intensive endeavor compared to use of aggregate level datawith issues
with deduplication plaguing many institutional databasesWithAmerican deaths recorded daily from
opioid overdoses and systems of care spread across multiple institutionsthe need for greater and high quality
data sharing is undeniableOur test partner for assessing the efficacy of proposed innovations is the Greater
Portland Addiction CollaborativeGPACin Mainea partnership of hospitalsa police departmentjaildetox
treatment centers and halfway houses already working together to reduce drug overdosesThis proposal aims
to demonstrate proof of concept foriscaling high quality data integrations across multiple governmental
domains via a standardized entity data modelandiiimproving record linkage using neural networksFirstlyOpenLattice is developing an open source ontology and integration scripts to standardize integration
of datasets into OpenLatticeandapos s databaseAs the individual customization requirements decline for onboarding
customers and integrating new data into the platformcosts will be greatly slashedremoving a significant
barrier to data solutions for smaller counties and cities across the countrywho have historically faced custom
integrationssystem updatesdata storage fees and add ons at high costThe OpenLattice platform also
enables use of existing ETL tools and seamless integration with police dispatch systemsemergency medical
callshealthcare recordsand online prescription systems across partners who have committed to data sharing
and collaborationSecondlyOpenLattice is developing a newproprietary algorithm for record linkage that
employs a promising but as yet commercially untested techniquea multilayer perceptron neural networkmore commonly known as deep learningIn pilot researchthe linking algorithm has already demonstrated
success rivaling and sometimes exceeding current state of the art linking technologiesIn Phase IOpenLattice will continue to improve ontologiesintegration toolsand the deep learning neural networkand
test on publicly available datasets with dissimilar data types and formatswith manual confirmation of resultsWhen successfulthese innovations will address critical barriers to improving clinical practice in treating
opioid addiction by enabling a more comprehensive continuum of care for those in treatment Project NarrativeLarge scale and coordinated responses to several of the US s hot button public health and
criminal justice issuessuch as the opioid epidemic and mass incarcerationare complicated by
poor resource sharing and the US government s highly fractured jurisdictional authorityThis
Small Business Innovation Research Phase I project aims to develop an efficientscalablecloudbased platform for hosting and linking highly sensitive state and local government databases at
low costusingiinnovative data integration scripts and ontologies that standardize and scale
capacity andiitechnical advances in record de duplication for linking databasesData
solutions would have tremendous societal impact on understandings of public health and the
opioid epidemic by making drug treatment less fracturedsaving lives and dramatically
broadening contextual informationonce data is broken out of silos

* Information listed above is at the time of submission. *

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