Cannabis Impairment Detection Application (CIDA)

NIH through NIDA solicits the research and development of digital markers for detection of marijuana intoxication and cognitive impairmentTo address the need for a validated method for quantifying impairment resulting from cannabis intoxicationthis project will implement an integratedsychophysiologicalcognitive behavioral and subjective report evaluation system programmed on an iPad using iOS ResearchKitAn easy to applywireless headset will acquire brain electrical activityEEGheart rate heart rate variabilitymovementand psychomotor responses to objectively probe the effects of cannabis during passive states and when participants are engaged in attentionverbal memory and executive function tasksThe ContractorAdvanced Brain Monitoringwill develop machine learning algorithms designed with an existing in house database and conduct a human subject study in partnership with the Subcontractorthe University of IowaThe iPad tests with concurrent psychophysiological recordings and a driving simulation scenario will be completed under three conditionsadministration of placebomg THCactivemg THCusing a VolcanoVaporization System with cannabis obtained from the NIDA Drug Supply Program