Passively Regulated Cryogenic (PaRC) Vial System for Vaccine Distribution and Administration

Award Information
Agency: Department of Defense
Branch: Defense Health Program
Contract: W81XWH-18-C-0075
Agency Tracking Number: H2-0274
Amount: $999,997.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: DHP163-003
Solicitation Number: 2016.3
Timeline
Solicitation Year: 2016
Award Year: 2018
Award Start Date (Proposal Award Date): 2018-03-05
Award End Date (Contract End Date): 2020-08-04
Small Business Information
200 Yellow Place, Rockledge, FL, 32955
DUNS: 175302579
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Dr. Josh Sole
 (321) 631-3552
 jsole@mainstream-engr.com
Business Contact
 Michael Rizzo
Phone: (321) 631-3500
Email: mar@mainstream-engr.com
Research Institution
N/A
Abstract
Warfighters in global regions endemic to vector-borne diseases, such as malaria, experience increased probability of being non-combatcasualties. Currently, a malaria vaccine is under development that requires cryogenic storage and transport (-150C or lower) and thereforedoes not readily integrate with existing vaccine distribution networks such as the World Health Organizations Expanded Program onImmunization protocol, which uses a 2C8C cold chain for distribution. To enable distribution of the new Plasmodium falciparum sporozoite(PfSPZ) malaria vaccine and other future eukaryotic cell vaccines that require cryopreservation, new technologies must be developed toenable vialing, cooling, transport, storage, rewarming, dilution, and administration to a patient in a cost-effective manner.Mainstreams Passively Regulated Cryogenic (PaRC) vial system for vaccine distribution is described in detail in this proposal.

* Information listed above is at the time of submission. *

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