Rapid Detection Nano-Sensors for Biological Warfare Agents in Buildings and HVAC Systems

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$749,941.00
Award Year:
2007
Program:
STTR
Phase:
Phase II
Contract:
W9132T-07-C-0022
Award Id:
77106
Agency Tracking Number:
A064-026-0064
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
590 Territorial Drive, Suite B, Bolingbrook, IL, 60440
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
068568588
Principal Investigator:
Dinakar Ramadurai
Biomedical Engineer
(630) 771-0203
rdinakar@epir.com
Business Contact:
Sivalingam Sivanantha
President
(630) 771-0201
ssivananthan@epir.com
Research Institute:
UNIV. OF ILLINOIS AT CHICAGO
Michael Stroscio
Office of Research Services
1737 W. Polk Street
Chicago, IL, 60612 7227
(312) 413-5968
Nonprofit college or university
Abstract
In the Phase I program, EPIR Technologies successfully developed a technology for real-time, simultaneous detection of several types of biological agents using a novel FRET-based detection technique. The development of multiplexed detection capabilities with extremely low false positives in this Phase I program allowed EPIR to establish improved standards in biosensing. Innovative surface modification protocols for bioconjugation of quencher labeled bioagents enabled the shelf life of these complexes to be extended greatly. In the proposed Phase II program, EPIR will develop the Phase I "proof of concept" to prototyping, while continuously working towards the advancement of the FRET-based detection to go beyond the current state of the art biosensors for HVAC systems. To sustain a commercially viable biosensor program, EPIR has already initiated the development of on-site facilities to lower production costs and expand process quality control. EPIR also proposes to investigate innovative design and engineering processes to develop low cost, miniature biosensors. Finally, EPIR proposes several innovative "smart decontamination" techniques that will be integrated to the biosensors to not only detect but also provide large scale, rapid decontamination of the air inside buildings and HVAC systems.

* information listed above is at the time of submission.

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