Agency: Department of Health and Human Services
Agency Tracking Number: N43ES201000006
Phase: Phase I
Awards Year: 2010
Solitcitation Year: 2010
Solitcitation Topic Code: NIEHS
Solitcitation Number: PHS2010-1
Small Business Information
LEADSCOPE, INC., 1393 DUBLIN RD, COLUMBUS, OH, 43215-
Hubzone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Name: Glenn Myatt
Phone: (614) 675-3768
AbstractThe last two decades have produced dramatic technological advances in molecular biology and computer science. The NTP is evaluating how best to incorporate these advances into its research and testing strategies in order to broaden scientific knowledge of exposure-related disease mechanisms. To support these efforts, the goal of this contract is to develop a PC and/or Mac-based integrated prediction system to support environment toxicological assessments. The developer will need to provide a user-friendly interface that will integrate tools commonly available for in silico predictions to provide data and predictions relating to the potential toxicological effects of a chemical of interest. The user must be able to enter a query via a Chemical Abstracts Service Registry Number, the chemical name, a structure data file, a molfile, a IUPAC International Chemical Identifier (InChl), or a Simplified Molecular Input Line Entry Systems (SMILES) code. Users must be able to limit their search criteria at least by toxicological endpoint (e.g., carcinogenicity, genotoxicity, immunotoxicity, reproductive toxicity).
* information listed above is at the time of submission.