MEASUREMENT SYSTEM FOR PASSIVE RESPIRATORY MECHANICS

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 3237
Amount: $81,000.00
Phase: Phase II
Program: SBIR
Awards Year: 1987
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Equilibrated Bio Systems, Inc.
900 Walt Whitman Road, Melville, NY, 11747
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Alex Stenzler
 Principal Investigator
 (516) 673-6660
Business Contact
Phone: () -
Research Institution
N/A
Abstract
THE LONG-TERM OBJECTIVE OF THE PROJECT IS TO DEVELOP AN AUTOMATED, SIMPLE-TO-USE SYSTEM FOR THE MEASUREMENT OF RESPIRATORY MECHANICS IN NEWBORNS AND CHILDREN WITH A PASSIVE EXPIRATORY MANEUVER. FLOW VOLUME MEASUREMENTS FOLLOWING RELAXATION OF THE RESPIRATORY MUSCLES WITH THE HERING-BREUER REFLEX ALLOW FOR CALCULATION OF TOTAL COMPLIANCE AND RESISTANCE USING THE END INSPIRATORY PLATEAU PRESSURE AS MEAN PLEURAL PRESSURE. PREVIOUSLY DESCRIBED APPLICATION OF THIS TECHNIQUE USED MANUAL CONTROLS FOR SHUTTER CLOSURE AND DATA ANALYSIS, EXCLUDING THE METHOD TO ONLY RESEARCH APPLICATIONS. SPECIAL DESIGN CONSIDERATIONS HAVE PROVISIONS FOR MANAGING THE LOW DEADSPACE REQUIREMENTS OF THE PATIENT POPULATION AND PRODUCING AIRWAY OCCLUSION WITHOUT INDUCING PRESSURE ARTIFACTS. AN AUTOMATED SYSTEM WOULD PLACE THIS TECHNIQUE WITHIN THE REACH OF CLINICIANS FOR THE DIAGNOSIS AND MANAGEMENT OF NEWBORNS AND INFANTS WITH ALTERED LUNG FUNCTION.

* information listed above is at the time of submission.

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