Hand-Carried Ultrasonic Coagulation Function Profiler

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-09-C-0051
Agency Tracking Number: A083-175-0440
Amount: $69,988.00
Phase: Phase I
Program: SBIR
Awards Year: 2009
Solicitation Year: 2008
Solicitation Topic Code: A08-175
Solicitation Number: 2008.3
Small Business Information
Luna Innovations Incorporated
1 Riverside Circle, Suite 400, Roanoke, VA, 24016
DUNS: 627132913
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Paul Panetta
 Principal Investigator
 (757) 224-5724
 submissions340@lunainnovations.com
Business Contact
 Angela Keen
Title: Senior Contracts Administrator
Phone: (540) 552-5128
Email: submissions340@lunainnovations.com
Research Institution
N/A
Abstract
Recent statistics suggest that up to one-third of military trauma victims have a blood coagulation defect that prevents traditional hemorrhage control measures from working. Unfortunately, clinical evidence of coagulopathy can be difficult to observe, while standard laboratory tests for coagulation function may take 30–60 min from blood sampling to availability of results even in ideal clinical settings. Viscoelastic measurements such as thromboelastography (TEG) provide a global test of coagulation function that has been shown to better correlate to risk of blood transfusion in trauma patients, and are more amenable to point of care testing, than laboratory tests. Further miniaturization of this technology is needed, however, for far-forward combat casualty care. In this Phase I, Luna will show that quantitative ultrasound can provide equivalent measurements of coagulation dynamics to the TEG using electronics amenable to a handheld device. This research, conducted in conjunction with Virginia Commonwealth University, will also show that ultrasonic particle sizing technology in development at Luna can provide additional data on the composition of blood relating to platelet count and activation using the same electronics and hardware.

* information listed above is at the time of submission.

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