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POC Blood Coagulopathy Monitor

Award Information
Agency: Department of Defense
Branch: Defense Health Program
Contract: W81XWH19C0138
Agency Tracking Number: H19A-001-0024
Amount: $162,445.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: DHA19A-001
Solicitation Number: 2019.1
Solicitation Year: 2019
Award Year: 2019
Award Start Date (Proposal Award Date): 2019-08-05
Award End Date (Contract End Date): 2020-03-04
Small Business Information
701 McMillian Way NW, Huntsville, AL, 35806
DUNS: 185169620
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Ketan Bhatt
 (256) 726-4800
Business Contact
 Tanu Singhal
Phone: (256) 726-4800
Research Institution
 Clemson University
 Diane Myers
 300 Brackett Hall

Clemson, AL, 29634
 (864) 656-2424
 Nonprofit college or university
Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause of preventable deaths. Viscoelastic tests such as thromboelastography and rotational thromboelastometry can monitor the dynamics of clot development, stabilization and dissolution and have been utilized for diagnosing early trauma coagulopathy, guiding blood transfusion and revealing patients prognosis. However, both tests require expensive and cumbersome instrumentation, and trained operators limiting their usability at point-of-care. The objective of the proposed effort is to develop a point-of-care (POC) blood coagulopathy monitor that provides viscoelastic measurements of blood samples. The POC system will be capable of providing multi-channel viscoelastic data similar to the mechanical measurement systems using fingerstick blood samples. Proof-of-concept of the POC monitor will be established in Phase I by testing with normal blood samples as well as samples that mimic different coagulopathies. Phase II research will focus on development and characterization of an alpha prototype for the handheld, ruggedized POC blood coagulopathy monitor.

* Information listed above is at the time of submission. *

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