Integrated ultrasound and digital mammography system

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R43CA100959-01
Agency Tracking Number: CA100959
Amount: $468,185.00
Phase: Phase I
Program: SBIR
Awards Year: 2003
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 (303) 410-2862
Business Contact
Phone: (303) 254-2525
Research Institution
DESCRIPTION (provided by applicant): The long term objective of this research application is to develop an integrated ultrasound and digital x-ray imaging system for screening and diagnostic mammography. Our primary hypothesis is that the simultaneous acquisition, and presentation of spatially correlated digital x-ray and ultrasound images of the breast will improve the inherent sensitivity and specificity of conventional screening mammography, particularly for patients with dense breasts, leading to a substantial reduction in missed cancers and unnecessary biopsies. A secondary hypothesis is that the proposed computerized acquisition of full-breast ultrasound images will decrease the operator-dependent variability of conventional free-hand breast sonography. Specific aims of Phase I research are to: (1) Develop a prototype integrated system designed to simultaneously acquire optimized breast ultrasound and digital mammography images; (2) Compare the imaging performance of the integrated system to the imaging performance of conventional dedicated breast ultrasound and full-field digital mammography systems; and (3) Develop and evaluate methods for spatial registration and display of simultaneously acquired breast ultrasound and digital mammography images. Phase I research will focus primarily on feasibility studies, utilizing ultrasound, x-ray and multi-modality breast phantoms to evaluate the performance of the integrated system over a limited field-of-view. Phase I research results will be used to develop several full-breast clinical prototypes in Phase II and to test the clinical outcome hypothesis indicated above.

* Information listed above is at the time of submission. *

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government