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Therapeutic in Situ Analgesic Implant for improved Oral-Facial Post-Operative Pain Outcomes

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R43DE029379-01
Agency Tracking Number: R43DE029379
Amount: $390,335.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: NIDCR
Solicitation Number: PA18-574
Timeline
Solicitation Year: 2018
Award Year: 2019
Award Start Date (Proposal Award Date): 2019-09-19
Award End Date (Contract End Date): 2020-09-18
Small Business Information
10225 BARNES CANYON RD, STE A104
San Diego, CA 92121-2734
United States
DUNS: 963248807
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 CRAIG FRIEDMAN
 (203) 216-8008
 cfriedman@epigenbiosciences.com
Business Contact
 GRAHAM BEATON
Phone: (858) 657-0918
Email: gbepigen@gmail.com
Research Institution
N/A
Abstract

PROJECT SUMMARY Analgesia for post operative populations remains a significant health need that calls for innovative therapies which improve both safety and outcome measuresRecent FDA drug safety warnings and studies focusing on post operative analgesia have highlighted the imperative need for new approaches that can be utilized for common clinical scenariosAccordinglynovel treatment options that are safe and afford additional benefit in relief of pain are neededIn this proposalthe development of an innovative surgical sealant technology is proposed that functions at the level of the surgical wound bed and actively delivers local pharmacologic agents to therapeutically address post operative painNew formulations of several analgesic regimens will be assessed for their ability to seal wounds and provide appropriate pain management Narrative The objective is to discover and develop a new therapeutic tissue sealant containing analgesics for the management of complications in oral surgical proceduresa leading cause of discomfort

* Information listed above is at the time of submission. *

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