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STTR Phase I: A Novel Device for Accurate Intrapartum Fetal Health Monitoring

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: 2015174
Agency Tracking Number: 2015174
Amount: $225,000.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: MD
Solicitation Number: N/A
Timeline
Solicitation Year: 2019
Award Year: 2020
Award Start Date (Proposal Award Date): 2020-05-01
Award End Date (Contract End Date): 2020-10-31
Small Business Information
2918 COHO PL
DAVIS, CA 95616
United States
DUNS: 117157062
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Soheil Ghiasi
 (530) 341-3493
 ghiasi@gmail.com
Business Contact
 Soheil Ghiasi
Phone: (530) 341-3493
Email: ghiasi@gmail.com
Research Institution
 University of California-Davis
 Aijun Wang
 
OR/Sponsored Programs 1850 Research Park Dr., Ste 300
Davis, CA 95618
United States

 Nonprofit College or University
Abstract

The broader impact/commercial potential of the proposed STTR Phase I project is to build a non-invasive medical device for fetal health monitoring to assist obstetricians in avoiding unnecessary cesarean-section surgeries (C-Sections). Despite significant cost and clear evidence of health risks associated with C-Sections, many infants are delivered via C-Sections. The high C-section rate and the associated additional cost and health complications result in part from inaccuracy of existing electronic fetal monitors, which generate many false alarms for fetal distress. The goal of this project is to address this problem by developing a non-invasive device so obstetricians may conveniently and accurately assess fetal health during labor and delivery. The proposed STTR Phase I project is to advance a breakthrough technology for non-invasive, transabdominal measurement of fetal arterial blood oxygen saturation (FSpO2). The underlying principle of operation is to shine light in the abdominal area at two specific near-infrared wavelengths and subsequently sense the small amount of diffusely scattered light transcutaneously. These measured signals require processing to correct for the maternal contribution and to infer intensity variations due to pulsation of fetal arteries. The proposed project will advance the development of a prototype and demonstrate feasibility of safe, robust and reliable transabdominal FSpO2 measurement in hypoxic fetal animal models. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

* Information listed above is at the time of submission. *

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