"STUDY OF LINKED GROWTH FACTOR GENES ON CHROMOSOME 5"

Award Information

Agency: Department of Health and Human Services

Branch: N/A

Contract: N/A

Agency Tracking Number: 8025

Amount: $500,000.00

Phase: Phase II

Program: SBIR

Solicitation Topic Code: N/A

Solicitation Number: N/A

Timeline

Solicitation Year: N/A

Award Year: 1991

Award Start Date (Proposal Award Date): N/A

Award End Date (Contract End Date): N/A

Small Business Information

GENELABS TECHNOLOGIES, INC.

505 Penobscot Dr

Redwood City, CA 94043

United States

DUNS: N/A

HUBZone Owned: No

Woman Owned: No

Socially and Economically Disadvantaged: No

Principal Investigator

Phone: () -

Business Contact

Phone: () -

Research Institution

N/A

Abstract

WE PROPOSE TO ISOLATE NEW GROWTH FACTOR OR GROWTH FACTOR RECEPTOR GENES, BASED UPON THEIR LINKAGE TO A CLUSTER OF SUCH GENES ON HUMAN CHROMOSOME 5. A LONG RANGE COMPARATIVE PHYSICAL MAP OF THE KNOWN GENES WITHIN THIS REGION WILL BE COMPILED, AND LARGE DNA FRAGMENTS ON WHICH TWO OR MORE OF THESE GENES RESIDE, WILL BE IDENTIFIED. PROBES SPECIFIC TO THESE FRAGMENTS WILL BE ISOLATED USING A COMBINATION OF SIZESELECTION AND INNOVATIVE CLONING TECHNOLOGIES. THIS MIXTUREOF PROBES WILL THEN BE USED TO SCREEN CDNA LIBRARIES FROM APPROPRIATE TISSUES IN ORDER TO IDENTIFY CANDIDATE GENES. IF NEW GROWTH FACTOR OR GROWTH FACTOR RECEPTOR GENES COULD BE ISOLATED IN THIS MANNER, THESE COULD BE OF CONSIDERABLE IMPORTANCE IN THE TREATMENT OF A NUMBER OF HEMATOPOIETIC DISORDERS AND VARIOUS FORMS OF NEOPLASIA.

* Information listed above is at the time of submission. *

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"STUDY OF LINKED GROWTH FACTOR GENES ON CHROMOSOME 5"