Automated Preferential Display for the Analysis of Gene Expression Profiles

Award Information
Agency:
Department of Defense
Branch
Office for Chemical and Biological Defense
Amount:
$69,900.00
Award Year:
2002
Program:
SBIR
Phase:
Phase I
Contract:
DAAD13-02-P-0039
Award Id:
58305
Agency Tracking Number:
C021-0020
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
PO Box 200759, Austin, TX, 78729
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
807519264
Principal Investigator:
RobertChin
President
(512) 659-4539
rchin@genexpressinfo.com
Business Contact:
RickyVirgne
CFO
(512) 990-1200
rvigne@swbell.net
Research Institute:
n/a
Abstract
"GeneXpress Informatics, Inc. (GXI) and Dr. James P. Chambers of UTSA propose to develop a revolutionary differential gene display technology, called Preferential Display (PD) which will provide for a simplified, cost-effective method to identify thesegenes for use in discovering gene expression profiles without having any prior knowledge of an organism, tissue or biological samples' genome. The technology utilizes a combination of biomolecular chemistry methods to eliminate redundant sequences andfluorescence dye assay to identify and isolate these unique sequences.In Phase I, GXI and Dr. Chambers propose to develop and demonstrate the PD technology by identifying unique gene sequences expressed by different cell or tissue types. In Phase II, GXI will develop PD benchtop high throughput system for rapid isolationand identification of unique gene expression profiles. Also included in the Phase II will be a lab-on-chip implementation of the PD technology for a future handheld biosensor application. GXI's Preferential Display is a breakthrough technology which is used to identify unique gene expression sequences of these cellular changes thus providing potentially new age related drug targets to pharmaceutical company end users."

* information listed above is at the time of submission.

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