Multi-IMmmunotoxicity Assay System (MIMAS)

Award Information
Agency:
Department of Defense
Branch
Air Force
Amount:
$99,938.00
Award Year:
2005
Program:
SBIR
Phase:
Phase I
Contract:
FA8650-05-M-6620
Agency Tracking Number:
F051-076-1396
Solicitation Year:
2005
Solicitation Topic Code:
AF05-076
Solicitation Number:
2005.1
Small Business Information
GENEXPRESS INFORMATICS, INC.
13091 Ponds Springs Road, Suite 150, Austin, TX, 78729
Hubzone Owned:
N
Socially and Economically Disadvantaged:
Y
Woman Owned:
N
Duns:
807519264
Principal Investigator:
Robert Chin
President
(512) 219-8588
rchin@genexpressinfo.com
Business Contact:
Ricky Virgne
CFO
(512) 496-5110
rvirgne@genexpressinfo.com
Research Institution:
n/a
Abstract
GeneXpress Informatics, Inc. (GXI) proposes to develop a Multi-IMmunotoxicity Assay System (MIMAS) based upon the Luminex Corporation (Austin, TX) xMAP system, a flexible analyzer based on the principles of flow cytometry. The proposed MIMAS will utilize three core technologies. The first is the Luminex xMAP microspheres, a family of 100 fluorescently dyed polystyrene microspheres that act as both the identifier and the solid surface to build the immunotoxic assays. The second is a handheld flow cytometry-based instrument, which integrates key xMAP detection components such as lasers, optics, advanced fluidics and high-speed digital signal processors. The third component is a disposal cartridge containing immuno-coded beads, assay incubation chambers and a flow cell. GXI and Dr. Claudia S. Miller of the University of Texas Health Science Center (UTHSC) will also identify immunotoxic biomarkers for bead assay development. In Phase I, GXI and Dr. Miller proposes to integrate immunotoxicity assays into a field portable MIMAS system. The Phase II program will result in a bench MIMAS prototype system for use in demonstrating the integration of these technology components. The envisioned MIMAS system will be used to assay human samples (i.e. blood, saliva, sweat).

* information listed above is at the time of submission.

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