GLUCOSE SENSOR WITH IMPROVED STABILITY

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$498,153.00
Award Year:
1990
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Agency Tracking Number:
7223
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Giner Inc.
14 Spring Street, Waltham, MA, 02154
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Srinivasam Sarangapani Ph
(617) 899-7270
Business Contact:
() -
Research Institution:
n/a
Abstract
THE DEVELOPMENT OF AN IMPLANTABLE GLUCOSE SENSOR COULD PROVIDE CLOSER CONTROL OF GLUCOSE LEVELS IN DIABETICS THAN IS NOW POSSIBLE. GLUCOSE SENSOR RESEARCH, USING A CATALYTICMETAL SENSOR BASED ON PLATINUM, IS CURRENTLY BEING PERFORMEDBY GINER, INC. CONSIDERABLE PROGRESS HAS BEEN MADE SO FAR IN IMPROVING THE SENSITIVITY AND SHORT-TERM STABILITY OF THESENSOR; IMPROVEMENTS IN SELECTIVITY TOWARD GLUCOSE IN THE PRESENCE OF COREACTANTS ARE UNDER WAY. THE PURPOSE OF THE PROPOSED RESEARCH IS TO IMPROVE THE LONGEVITY OF ELECTROCATALYTIC GLUCOSE SENSORS BASED ON PLATINUM. MAINTENANCE OF A SENSOR RESPONSE AT A CONSTANT LEVEL OVER AN EXTENDED PERIOD OF TIME IS DESIRABLE, BECAUSE IT AVOIDS THE NEED FOR FREQUENT CALIBRATION. PRELIMINARY STUDIES WITH SPECIALLY FORMULATED POLYMER-BONDED, PLATINUM BLACK ELECTRODES SHOW IMPROVED STABILITY. THE PROPOSED WORKATTEMPTS TO DEVELOP THIS CONCEPT FURTHER AND PROVE ITS FEASIBILITY THROUGH RIGOROUS TESTING AND ANALYSIS.

* information listed above is at the time of submission.

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